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1

Cyclodextrin-based pharmaceutics: past, present and future

Davis, Mark E., Brewster, Marcus E.

Journal:

Nature Reviews Drug Discovery

Year:

2004

Language:

english

File:

PDF, 251 KB

english, 2004

2

[Biotechnology: Pharmaceutical Aspects] Solvent Systems and Their Selection in Pharmaceutics and Biopharmaceutics Volume 5H || Solubilizing Systems for Parenteral Formulation Development—Small Molecules

Augustijns, Patrick, Brewster, Marcus E.

Year:

2007

Language:

english

File:

PDF, 370 KB

english, 2007

3

In vivo methods for drug absorption – Comparative physiologies, model selection, correlations with in vitro methods (IVIVC), and applications for formulation/API/excipient characterization including food effects

Sjögren, Erik, Abrahamsson, Bertil, Augustijns, Patrick, Becker, Dieter, Bolger, Michael B., Brewster, Marcus, Brouwers, Joachim, Flanagan, Talia, Harwood, Matthew, Heinen, Christian, Holm, René, Jure

Journal:

European Journal of Pharmaceutical Sciences

Year:

2014

Language:

english

File:

PDF, 5.20 MB

english, 2014

4

Summary Report of PQRI Workshop on Nanomaterial in Drug Products: Current Experience and Management of Potential Risks

Bartlett, Jeremy A., Brewster, Marcus, Brown, Paul, Cabral-Lilly, Donna, Cruz, Celia N., David, Raymond, Eickhoff, W. Mark, Haubenreisser, Sabine, Jacobs, Abigail, Malinoski, Frank, Morefield, Elaine,

Journal:

The AAPS Journal

Year:

2015

Language:

english

File:

PDF, 1.90 MB

english, 2015

5

[Biotechnology: Pharmaceutical Aspects] Solvent Systems and Their Selection in Pharmaceutics and Biopharmaceutics || Solvent Systems for Crystallization and Polymorph Selection

Augustijns, Patrick, Brewster, Marcus E.

Year:

2007

Language:

english

File:

PDF, 787 KB

english, 2007

6

Synthesis of deuterated dexanabinol, a nonpsychotropic cannabinoid with neuroprotective properties

Emil Pop, Bogumila Rachwal, Stanislaw Rachwal, Jirina Vlasak, Marcus E. Brewster, Laszlo Prokai

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

1998

File:

PDF, 528 KB

1998

7

The use of three different solid dispersion formulations—melt extrusion, film-coated beads, and a glass thermoplastic system—to improve the bioavailability of a novel microsomal triglyceride transfer protein inhibitor

Geert Verreck, Roger Vandecruys, Val De Conde, Lieven Baert, Jef Peeters, Marcus E. Brewster

Journal:

Journal of Pharmaceutical Sciences

Year:

2004

Language:

english

File:

PDF, 252 KB

english, 2004

8

Self-assembly of cyclodextrins: The effect of the guest molecule

Martin Messner, Sergey V. Kurkov, Ramon Flavià-Piera, Marcus E. Brewster, Thorsteinn Loftsson

Journal:

International Journal of Pharmaceutics

Year:

2011

Language:

english

File:

PDF, 1.24 MB

english, 2011

9

Self-assembly of cyclodextrin complexes: Aggregation of hydrocortisone/cyclodextrin complexes

Martin Messner, Sergey V. Kurkov, Marcus E. Brewster, Phatsawee Jansook, Thorsteinn Loftsson

Journal:

International Journal of Pharmaceutics

Year:

2011

Language:

english

File:

PDF, 892 KB

english, 2011

10

Derivatives of Dexanabinol. I. Water-Soluble Salts of Glycinate Esters

Emil Pop, Zong Zheng Liu, Marcus E. Brewster, Yechezkel Barenholz, Veronica Korablyov, Raphael Mechoulam, Varda Nadler, Anat Biegon

Journal:

Pharmaceutical Research

Year:

1996

File:

PDF, 1.40 MB

1996

11

High-speed digital imaging method for ciliary beat frequency measurement

Svetlana Dimova, Frederik Maes, Marcus E. Brewster, Mark Jorissen, Mark Noppe, Patrick Augustijns

Journal:

Journal of Pharmacy and Pharmacology

Year:

2005

Language:

english

File:

PDF, 131 KB

english, 2005

12

Cyclodextrins as functional excipients: Methods to enhance complexation efficiency

Thorsteinn Loftsson, Marcus E. Brewster

Journal:

Journal of Pharmaceutical Sciences

Year:

2012

Language:

english

File:

PDF, 431 KB

english, 2012

13

Self-assembly of cyclodextrin complexes: Effect of temperature, agitation and media composition on aggregation

Martin Messner, Sergey V. Kurkov, Marta Maraver Palazón, Berta Álvarez Fernández, Marcus E. Brewster, Thorsteinn Loftsson

Journal:

International Journal of Pharmaceutics

Year:

2011

Language:

english

File:

PDF, 814 KB

english, 2011

14

Modified poly(propylene imine) dendrimers as effective transfection agents for catalytic DNA enzymes (DNAzymes)

Tack, Frederik, Bakker, Annette, Maes, Sophie, Dekeyser, Nathalie, Bruining, Monique, Elissen-Roman, Cristina, Janicot, Michel, Brewster, Marcus, Janssen, Henk M., De Waal, B. F. M., Fransen, P. M., L

Journal:

Journal of Drug Targeting

Year:

2006

Language:

english

File:

PDF, 944 KB

english, 2006

15

Pharmaceutical applications of cyclodextrins: basic science and product development

Thorsteinn Loftsson, Marcus E. Brewster

Journal:

Journal of Pharmacy and Pharmacology

Year:

2010

Language:

english

File:

PDF, 464 KB

english, 2010

16

In vitro models for the prediction of in vivo performance of oral dosage forms

Kostewicz, Edmund S., Abrahamsson, Bertil, Brewster, Marcus, Brouwers, Joachim, Butler, James, Carlert, Sara, Dickinson, Paul A., Dressman, Jennifer, Holm, René, Klein, Sandra, Mann, James, McAllister

Journal:

European Journal of Pharmaceutical Sciences

Year:

2014

Language:

english

File:

PDF, 1.41 MB

english, 2014

17

[Biotechnology: Pharmaceutical Aspects] Solvent Systems and Their Selection in Pharmaceutics and Biopharmaceutics ||

Augustijns, Patrick, Brewster, Marcus E.

Year:

2007

Language:

english

File:

PDF, 7.15 MB

english, 2007

18

[Biotechnology: Pharmaceutical Aspects] Solvent Systems and Their Selection in Pharmaceutics and Biopharmaceutics || Biorelevant Dissolution Media

Augustijns, Patrick, Brewster, Marcus E.

Year:

2007

Language:

english

File:

PDF, 431 KB

english, 2007

19

Early pharmaceutical profiling to predict oral drug absorption: Current status and unmet needs

Bergström, Christel A.S., Holm, René, Jørgensen, Søren Astrup, Andersson, Sara B.E., Artursson, Per, Beato, Stefania, Borde, Anders, Box, Karl, Brewster, Marcus, Dressman, Jennifer, Feng, Kung-I., Hal

Journal:

European Journal of Pharmaceutical Sciences

Year:

2014

Language:

english

File:

PDF, 1.68 MB

english, 2014

20

[Biotechnology: Pharmaceutical Aspects] Solvent Systems and Their Selection in Pharmaceutics and Biopharmaceutics || Practical Aspects of Solubility Determination in Pharmaceutical Preformulation

Augustijns, Patrick, Brewster, Marcus E.

Year:

2007

Language:

english

File:

PDF, 237 KB

english, 2007

21

A Preclinical Bioavailability Strategy for Decisions on Clinical Drug Formulation Development: an In Depth Analysis

Van Den Bergh, An, Van Hemelryck, Sandy, Bevernage, Jan, Van Peer, Achiel, Brewster, Marcus, Mackie, Claire, Mannaert, Erik

Journal:

Molecular Pharmaceutics

Year:

2018

Language:

english

File:

PDF, 1.77 MB

english, 2018

22

AM1-based model system for estimation of brain / blood concentration ratios

Marcus E. Brewster, Emil Pop, Ming-Ju Huang, Nicholas Bodor

Journal:

International Journal of Quantum Chemistry

Year:

1996

Language:

english

File:

PDF, 727 KB

english, 1996

23

Allylic rearrangement of trans-pinocarveol esters

Emil Pop, Stanislaw Rachwal, Marcus E. Brewster

Journal:

International Journal of Quantum Chemistry

Year:

1996

Language:

english

File:

PDF, 426 KB

english, 1996

24

Dimerization of dexanabinol by hydrogen bonding accounts for its hydrophobic character

Emil Pop, Marcus E. Brewster

Journal:

International Journal of Quantum Chemistry

Year:

1997

Language:

english

File:

PDF, 227 KB

english, 1997

25

Reactivity of biologically important reduced pyridines. VIII. A semiempirical (AM1) study of the oxidation of 3-substituted-1-methyl-1,4-dihydropyridines

Marcus E. Brewster, Ming-Ju Huang, James J. Kaminski, Emil Pop, Nicholas Bodor

Journal:

Journal of Computational Chemistry

Year:

1991

Language:

english

File:

PDF, 438 KB

english, 1991

26

Characterization of the interaction of 2-hydroxypropyl-β-cyclodextrin with itraconazole at pH 2, 4, and 7

Jef Peeters, Peter Neeskens, Jan P. Tollenaere, Pieter Van Remoortere, Marcus E. Brewster

Journal:

Journal of Pharmaceutical Sciences

Year:

2002

Language:

english

File:

PDF, 140 KB

english, 2002

27

Increased physical stability and improved dissolution properties of itraconazole, a class II drug, by solid dispersions that combine fast- and slow-dissolving polymers

Karel Six, Geert Verreck, Jef Peeters, Marcus Brewster, Guy Van den Mooter

Journal:

Journal of Pharmaceutical Sciences

Year:

2004

Language:

english

File:

PDF, 131 KB

english, 2004

28

Self-association of cyclodextrins and cyclodextrin complexes

Thorsteinn Loftsson, Már Másson, Marcus E. Brewster

Journal:

Journal of Pharmaceutical Sciences

Year:

2004

Language:

english

File:

PDF, 113 KB

english, 2004

29

Usefulness of a novel Caco-2 cell perfusion system. I. in vitro prediction of the absorption potential of passively diffused compounds

Chantal Masungi, Caroline Borremans, Bart Willems, Jurgen Mensch, Alex Van Dijck, Patrick Augustijns, Marcus E. Brewster, Mark Noppe

Journal:

Journal of Pharmaceutical Sciences

Year:

2004

Language:

english

File:

PDF, 533 KB

english, 2004

30

Effects of cyclodextrins on drug delivery through biological membranes

Thorsteinn Loftsson, Stine Byskov Vogensen, Marcus E. Brewster, Fífa Konráðsdóttir

Journal:

Journal of Pharmaceutical Sciences

Year:

2007

Language:

english

File:

PDF, 199 KB

english, 2007

31

Supersaturating drug delivery systems: The answer to solubility-limited oral bioavailability?

Joachim Brouwers, Marcus E. Brewster, Patrick Augustijns

Journal:

Journal of Pharmaceutical Sciences

Year:

2009

Language:

english

File:

PDF, 648 KB

english, 2009

32

Physicochemical properties of the amorphous drug, cast films, and spray dried powders to predict formulation probability of success for solid dispersions: Etravirine

Ilse Weuts, Frederic Van Dycke, Jody Voorspoels, Steve De Cort, Sigrid Stokbroekx, Ruud Leemans, Marcus E. Brewster, Dawei Xu, Brigitte Segmuller, Ya Tsz A. Turner, Clive J. Roberts, Martyn C. Davies,

Journal:

Journal of Pharmaceutical Sciences

Year:

2011

Language:

english

File:

PDF, 1.46 MB

english, 2011

33

Supersaturating drug delivery systems: Fast is not necessarily good enough

Patrick Augustijns, Marcus E. Brewster

Journal:

Journal of Pharmaceutical Sciences

Year:

2012

Language:

english

File:

PDF, 53 KB

english, 2012

34

Improved delivery through biological membranes XXXI: Solubilization and stabilization of an estradiol chemical delivery system by modified β-cyclodextrins

Marcus E. Brewster, Kerry S. Estes, Thorsteinn Loftsson, Robert Perchalski, Hartmut Derendorf, Gotelind Mullersman, Nicholas Bodor

Journal:

Journal of Pharmaceutical Sciences

Year:

1988

Language:

english

File:

PDF, 586 KB

english, 1988

35

Redox derivatives of tranylcypromine: Syntheses, properties, and monoamine oxidase inhibitor activity of some chemical delivery systems

Katalin Prókai-Tátrai, Emil Pop, Wesley Anderson, Jun-Liang Lin, Marcus E. Brewster, Nicholas Bodor

Journal:

Journal of Pharmaceutical Sciences

Year:

1991

Language:

english

File:

PDF, 769 KB

english, 1991

36

Development of aqueous parenteral formulations for carbamazepine through the use of modified cyclodextrins

Marcus E. Brewster, Wesley R. Anderson, Kerry S. Estes, Nicholas Bodor

Journal:

Journal of Pharmaceutical Sciences

Year:

1991

Language:

english

File:

PDF, 590 KB

english, 1991

37

Brain, blood, and cerebrospinal fluid distribution of a zidovudine chemical delivery system in rabbits

Marcus E. Brewster, Wesley Anderson, Nicholas Bodor

Journal:

Journal of Pharmaceutical Sciences

Year:

1991

Language:

english

File:

PDF, 373 KB

english, 1991

38

Efficacy of a 3-substituted versus 17-substituted chemical delivery system for estradiol brain targeting

Marcus E. Brewster, Pascal J. Druzgala, Wesley R. Anderson, Ming-Ju Huang, Nicholas Bodor, Emil Pop

Journal:

Journal of Pharmaceutical Sciences

Year:

1995

Language:

english

File:

PDF, 773 KB

english, 1995

39

Tissue distribution of LY231617, an antioxidant with neuroprotectant activity, in the rat

Marcus E. Brewster, Wesley R. Anderson, Emil Pop, Nicholas S. Bodor, Jill A. Panetta, Kerry S. Estes

Journal:

Journal of Pharmaceutical Sciences

Year:

1995

Language:

english

File:

PDF, 341 KB

english, 1995

40

Preparation, characterization, and anesthetic properties of 2-hydroxypropyl-β-cyclodextrin complexes of pregnanolone and pregnenolone in rat and mouse

Marcus E. Brewster, Wesley R. Anderson, Thorsteinn Loftsson, Ming-Ju Huang, Nicholas Bodor, Emil Pop

Journal:

Journal of Pharmaceutical Sciences

Year:

1995

Language:

english

File:

PDF, 809 KB

english, 1995

41

Hot stage extrusion of p-amino salicylic acid with EC using CO2 as a temporary plasticizer

Geert Verreck, Annelies Decorte, Koen Heymans, Jef Adriaensen, Dehua Liu, David Tomasko, Albertina Arien, Jef Peeters, Guy Van den Mooter, Marcus E. Brewster

Journal:

International Journal of Pharmaceutics

Year:

2006

Language:

english

File:

PDF, 322 KB

english, 2006

42

Effect of the unstirred water layer on permeability enhancement by hydrophilic cyclodextrins

Marcus E. Brewster, Marc Noppe, Jef Peeters, Thorsteinn Loftsson

Journal:

International Journal of Pharmaceutics

Year:

2007

Language:

english

File:

PDF, 120 KB

english, 2007

43

Use of a screening method to determine excipients which optimize the extent and stability of supersaturated drug solutions and application of this system to solid formulation design

Roger Vandecruys, Jef Peeters, Geert Verreck, Marcus E. Brewster

Journal:

International Journal of Pharmaceutics

Year:

2007

Language:

english

File:

PDF, 806 KB

english, 2007

44

Physicochemical properties of water and its effect on drug delivery: A commentary

Thorsteinn Loftsson, Marcus E. Brewster

Journal:

International Journal of Pharmaceutics

Year:

2008

Language:

english

File:

PDF, 603 KB

english, 2008

45

Active and passive tumor targeting of a novel poorly soluble cyclin dependent kinase inhibitor, JNJ-7706621

Fabienne Danhier, Bernard Ucakar, Nicolas Magotteaux, Marcus E. Brewster, Véronique Préat

Journal:

International Journal of Pharmaceutics

Year:

2010

Language:

english

File:

PDF, 910 KB

english, 2010

46

Application of PAMPA-models to predict BBB permeability including efflux ratio, plasma protein binding and physicochemical parameters

Jurgen Mensch, Libuse Jaroskova L, Wendy Sanderson, Anouche Melis, Claire Mackie, Geert Verreck, Marcus E. Brewster, Patrick Augustijns

Journal:

International Journal of Pharmaceutics

Year:

2010

Language:

english

File:

PDF, 488 KB

english, 2010

47

Novel generic UPLC/MS/MS method for high throughput analysis applied to permeability assessment in early Drug Discovery

Jurgen Mensch, Mark Noppe, Jef Adriaensen, Anouche Melis, Claire Mackie, Patrick Augustijns, Marcus E Brewster

Journal:

Journal of Chromatography B

Year:

2007

Language:

english

File:

PDF, 226 KB

english, 2007

48

The effect of pressurized carbon dioxide as a plasticizer and foaming agent on the hot melt extrusion process and extrudate properties of pharmaceutical polymers

Geert Verreck, Annelies Decorte, Hongbo Li, David Tomasko, Albertina Arien, Jef Peeters, Patrick Rombaut, Guy Van den Mooter, Marcus E. Brewster

Journal:

The Journal of Supercritical Fluids

Year:

2006

Language:

english

File:

PDF, 1.01 MB

english, 2006

49

The effect of supercritical CO2 as a reversible plasticizer and foaming agent on the hot stage extrusion of itraconazole with EC 20 cps

Geert Verreck, Annelies Decorte, Koen Heymans, Jef Adriaensen, Dehua Liu, David L. Tomasko, Albertina Arien, Jef Peeters, Patrick Rombaut, Guy Van den Mooter, Marcus E. Brewster

Journal:

The Journal of Supercritical Fluids

Year:

2007

Language:

english

File:

PDF, 977 KB

english, 2007

50

Reactivity of biologically important reduced pyridines VI. Lack of through-resonance stabilization in the ferricyanide-mediated oxidation of substituted 1-Phenyl-1,4-Dihydronicotinamides

Marcus E. Brewster, James J. kaminski, Zoltan Gabanyi, Klara Czako, Agnes Simay, Nicholas Bodor

Journal:

Year:

1990

Language:

english

File:

PDF, 436 KB

english, 1990

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